Evaluation of some Hematological Changes among Chronic Renal Failure Patients in Qatan Hospital, Hadhramout Governorate - Yemen

Authors

  • Abdulrahman Salem Yaseen Assitant prof. of Animal physiology Department of Biology, College of Sciences, Hadhramout University, Yemen. Received on 9/10/2020 and Accepted for Publication on 27/12/2020
  • Mohammed Ali Al-Maseeli Assitant prof. of Animal physiology Department of Biology, College of Sciences, Hadhramout University, Yemen. Received on 9/10/2020 and Accepted for Publication on 27/12/2020

Keywords:

Chronic renal failure, Hemodialysis, Hematological changes, Hadhramout

Abstract

This study was achieved at the industrial kidney center in Qatan hospital during the period from February 2018 to
July 2018, the study aimed at evaluating some hematological changes that occur in patients with chronic renal failure
(CRF) undergoing hemodialysis and comparing them with healthy people. Blood sample of 55 cases of both sexes
were collected: 35 patients with CRF and on regular maintenance dialysis, and a control group of 20 healthy persons
for comparison, in the age group ranged between 25-70 years for both groups. Hemoglobin concentration, total red
cells count, packed cell volume, total white blood cells count, neutrophils and lymphocytes differential count and
platelets count were assessed by using Sysmex hematology analyzer. Data was analyzed through statistical package
for social sciences (SPSS) version 24. Results recorded a significant decrease (p<0.05) in Hemoglobin concentration,
total red cells count, packed cell volume and platelets count in patients with CRF compared to the healthy group.
Although the total white blood cells count did not record any significant change, the differential count of
lymphocytes decreased significantly (p<0.05), and the differential count of neutrophils increased without significant
differences in patients with chronic renal failure CRF compared to healthy subjects. In conclusion, the present
findings suggested that the chronic renal failure CRF had a negative effect in most of hematological parameters under
study. Therefore, hematological parameters that need careful evaluation and management in chronic renal failure
CRF patients.

Downloads

Published

2023-11-22