Association of Varicocelectomy and Secondary Infertility Improvement among Yemeni Patients in Aden

Abstract

Background: Varicocele is believed to be the most
important factor in secondary male infertility.
Objective: The objective was to investigate the
association of varicocelectomy with improvement
of semen parameters and pregnancy rate post- varicocelectomy among Yemeni men with secondary
infertility.
Materials and method: The study was a prospective non-controlled trail conducted on Yemeni men
during the period of January 2012 to December
2014 who attended Algamhoria Teaching Hospital and Al-Saeedi hospital, in Aden for infertility
treatment.
Results: The total study subjects was 100 men
with varicocele, secondary infertility and reduced
semen parameters. The mean age of the patients
was 33.7 ± 7.7 years. Doppler Ultrasound categorized varicocele into Grade I (20%), Grade II
(48%), and Grade III (32%). The majority (70%)
of participants had varicocele on the left side. The
preoperative semen results showed that the average of total sperm number and motility were 17.84
± 5.64 x 106 and 19.19 ± 6.17 %, respectively.
Varicocelectomy lead to 80%, and 78% improvements in semen total number and motility of the
study men respectively, and they were collectively
showed significant higher pregnancy rate. Pregnancy had occurred in 63 (78.8%) and 61 (78.2%)
of women whom partners showed improvements
in semen total number (Phi = 0.26, P = 0.022) or
semen total motility (Phi = 0.23, P = 0.042), respectively.
Conclusion: The study confirmed the association of varicocele with secondary male infertility.
However, more controlled randomized clinical trials and biomedical studies are necessary to establish the causal relationship between varicocele and
male infertility.