Silver-Russell Syndrome

A case Report of Three Years Old Yemeni Boy

Abstract

Silver Russell Syndrome (SRS) is a rare condition. For diagnosis of SRS at least four of the following criteria should
be present which are intrauterine growth retardation , postnatal growth retardation , preservation of occipitofrontal
head circumference, classic facial phenotype (broad prominent forehead with small triangular face, small narrow chin
and low set ears) and body asymmetry. There is no data about cases of SRS reported in Yemen. We present a three
years old Yemeni boy with SRS. He is the first child of Yemeni consanguineous parent‟s average length. He is born
following normal pregnancy. The boy fulfilled the criteria proposed by Price et al and Azzi et al for diagnosis of
SRS but have no body asymmetry nor feeding difficulty. The patient was diagnosed as SRS on clinical ground. Chest
X-rays, Echocardiography and hormonal analysis had no significant results. Genetic analysis had not done because it
is not available at Yemen.